The 2B subdomain of Rep helicase links translocation along DNA with protein displacement

Helicases catalyse DNA and RNA strand separation. Proteins bound to the nucleic acid must also be displaced in order to unwind DNA. This is exemplified by accessory helicases that clear protein barriers from DNA ahead of advancing replication forks. How helicases catalyse DNA unwinding is increasing...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Brüning, Jan-Gert, Howard, Jamieson A L, Myka, Kamila K, Dillingham, Mark S, McGlynn, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158625/
https://ncbi.nlm.nih.gov/pubmed/30060236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky673
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