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Overexpression of the Replicative Helicase in Escherichia coli Inhibits Replication Initiation and Replication Fork Reloading

Replicative helicases play central roles in chromosome duplication and their assembly onto DNA is regulated via initiators and helicase loader proteins. The Escherichia coli replicative helicase DnaB and the helicase loader DnaC form a DnaB(6)–DnaC(6) complex that is required for loading DnaB onto s...

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Publicado en:J Mol Biol
Main Authors: Brüning, Jan-Gert, Myka, Kamila Katarzyna, McGlynn, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828956/
https://ncbi.nlm.nih.gov/pubmed/26812209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.01.018
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