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Protein–DNA complexes are the primary sources of replication fork pausing in Escherichia coli

Replication fork pausing drives genome instability, because any loss of paused replisome activity creates a requirement for reloading of the replication machinery, a potentially mutagenic process. Despite this importance, the relative contributions to fork pausing of different replicative barriers r...

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Detalhes bibliográficos
Main Authors: Gupta, Milind K., Guy, Colin P., Yeeles, Joseph T. P., Atkinson, John, Bell, Hazel, Lloyd, Robert G., Marians, Kenneth J., McGlynn, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645559/
https://ncbi.nlm.nih.gov/pubmed/23589869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303890110
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