Direct removal of RNA polymerase barriers to replication by accessory replicative helicases

Bacterial genome duplication and transcription require simultaneous access to the same DNA template. Conflicts between the replisome and transcription machinery can lead to interruption of DNA replication and loss of genome stability. Pausing, stalling and backtracking of transcribing RNA polymerase...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Hawkins, Michelle, Dimude, Juachi U, Howard, Jamieson A L, Smith, Abigail J, Dillingham, Mark S, Savery, Nigel J, Rudolph, Christian J, McGlynn, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547429/
https://ncbi.nlm.nih.gov/pubmed/30869136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz170
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