The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase

The PcrA/UvrD helicase functions in multiple pathways that promote bacterial genome stability including the suppression of conflicts between replication and transcription and facilitating the repair of transcribed DNA. The reported ability of PcrA/UvrD to bind and backtrack RNA polymerase (1,2) migh...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Sanders, Kelly, Lin, Chia-Liang, Smith, Abigail J., Cronin, Nora, Fisher, Gemma, Eftychidis, Vasileios, McGlynn, Peter, Savery, Nigel J., Wigley, Dale B., Dillingham, Mark S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397179/
https://ncbi.nlm.nih.gov/pubmed/28160601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx074
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