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A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication
Replication of sufficient mitochondrial DNA (mtDNA) is essential for maintaining mitochondrial functions in mammalian cells. During mtDNA replication, RNA primers must be removed before the nascent circular DNA strands rejoin. This process involves mitochondrial RNase H1, which removes most of the R...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547421/ https://ncbi.nlm.nih.gov/pubmed/30949702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz241 |
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