A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication

Replication of sufficient mitochondrial DNA (mtDNA) is essential for maintaining mitochondrial functions in mammalian cells. During mtDNA replication, RNA primers must be removed before the nascent circular DNA strands rejoin. This process involves mitochondrial RNase H1, which removes most of the R...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Wu, Chyuan-Chuan, Lin, Jason L J, Yang-Yen, Hsin-Fang, Yuan, Hanna S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Structural Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547421/
https://ncbi.nlm.nih.gov/pubmed/30949702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz241
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