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Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer

Human exonuclease 1 (EXO1), a 5′→3′ exonuclease, contributes to the regulation of the cell cycle checkpoints, replication fork maintenance, and post replicative DNA repair pathways. These processes are required for the resolution of stalled or blocked DNA replication that can lead to replication str...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Keijzers, Guido, Bakula, Daniela, Petr, Michael Angelo, Madsen, Nils Gedsig Kirkelund, Teklu, Amanuel, Mkrtchyan, Garik, Osborne, Brenna, Scheibye-Knudsen, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337416/
https://ncbi.nlm.nih.gov/pubmed/30585186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010074
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