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Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer

Human exonuclease 1 (EXO1), a 5′→3′ exonuclease, contributes to the regulation of the cell cycle checkpoints, replication fork maintenance, and post replicative DNA repair pathways. These processes are required for the resolution of stalled or blocked DNA replication that can lead to replication str...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Keijzers, Guido, Bakula, Daniela, Petr, Michael Angelo, Madsen, Nils Gedsig Kirkelund, Teklu, Amanuel, Mkrtchyan, Garik, Osborne, Brenna, Scheibye-Knudsen, Morten
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337416/
https://ncbi.nlm.nih.gov/pubmed/30585186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010074
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