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Human exonuclease 1 (EXO1) activity characterization and its function on flap structures

Human exonuclease 1 (EXO1) is involved in multiple DNA metabolism processes, including DNA repair and replication. Most of the fundamental roles of EXO1 have been described in yeast. Here, we report a biochemical characterization of human full-length EXO1. Prior to assay EXO1 on different DNA flap s...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Keijzers, Guido, Bohr, Vilhelm A., Rasmussen, Lene Juel
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613700/
https://ncbi.nlm.nih.gov/pubmed/26182368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150058
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