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Highly stable hexitol based XNA aptamers targeting the vascular endothelial growth factor
Biomedical applications of nucleic acid aptamers are limited by their rapid degradation in biological fluids and generally demand tedious post-selection modifications that might compromise binding. One possible solution to warrant biostability is to directly evolve chemically modified aptamers from...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547419/ https://ncbi.nlm.nih.gov/pubmed/30968117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz252 |
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