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In vitro selection of an XNA aptamer capable of small-molecule recognition

Despite advances in XNA evolution, the binding capabilities of artificial genetic polymers are currently limited to protein targets. Here, we describe the expansion of in vitro evolution techniques to enable selection of threose nucleic acid (TNA) aptamers to ochratoxin A (OTA). This research establ...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Rangel, Alexandra E, Chen, Zhe, Ayele, Tewoderos M, Heemstra, Jennifer M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144807/
https://ncbi.nlm.nih.gov/pubmed/30085205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky667
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