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In vitro selection of an XNA aptamer capable of small-molecule recognition

Despite advances in XNA evolution, the binding capabilities of artificial genetic polymers are currently limited to protein targets. Here, we describe the expansion of in vitro evolution techniques to enable selection of threose nucleic acid (TNA) aptamers to ochratoxin A (OTA). This research establ...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Rangel, Alexandra E, Chen, Zhe, Ayele, Tewoderos M, Heemstra, Jennifer M
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144807/
https://ncbi.nlm.nih.gov/pubmed/30085205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky667
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