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Highly stable hexitol based XNA aptamers targeting the vascular endothelial growth factor
Biomedical applications of nucleic acid aptamers are limited by their rapid degradation in biological fluids and generally demand tedious post-selection modifications that might compromise binding. One possible solution to warrant biostability is to directly evolve chemically modified aptamers from...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547419/ https://ncbi.nlm.nih.gov/pubmed/30968117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz252 |
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