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Genetic Variation in LPA, Calcific Aortic Valve Stenosis in Patients Undergoing Cardiac Surgery, and Familial Risk of Aortic Valve Microcalcification

IMPORTANCE: Genetic variants at the LPA locus are associated with both calcific aortic valve stenosis (CAVS) and coronary artery disease (CAD). Whether these variants are associated with CAVS in patients with CAD vs those without CAD is unknown. OBJECTIVE: To study the associations of LPA variants w...

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Bibliografische gegevens
Gepubliceerd in:JAMA Cardiol
Hoofdauteurs: Perrot, Nicolas, Thériault, Sébastien, Dina, Christian, Chen, Hao Yu, Boekholdt, S. Matthijs, Rigade, Sidwell, Després, Audrey-Anne, Poulin, Anthony, Capoulade, Romain, Le Tourneau, Thierry, Messika-Zeitoun, David, Trottier, Mikaël, Tessier, Michel, Guimond, Jean, Nadeau, Maxime, Engert, James C., Khaw, Kay-Tee, Wareham, Nicholas J., Dweck, Marc R., Mathieu, Patrick, Pibarot, Philippe, Schott, Jean-Jacques, Thanassoulis, George, Clavel, Marie-Annick, Bossé, Yohan, Arsenault, Benoit J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Medical Association 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547086/
https://ncbi.nlm.nih.gov/pubmed/31141105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2019.1581
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