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Genetic Variation in LPA, Calcific Aortic Valve Stenosis in Patients Undergoing Cardiac Surgery, and Familial Risk of Aortic Valve Microcalcification

IMPORTANCE: Genetic variants at the LPA locus are associated with both calcific aortic valve stenosis (CAVS) and coronary artery disease (CAD). Whether these variants are associated with CAVS in patients with CAD vs those without CAD is unknown. OBJECTIVE: To study the associations of LPA variants w...

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Bibliografiske detaljer
Udgivet i:JAMA Cardiol
Main Authors: Perrot, Nicolas, Thériault, Sébastien, Dina, Christian, Chen, Hao Yu, Boekholdt, S. Matthijs, Rigade, Sidwell, Després, Audrey-Anne, Poulin, Anthony, Capoulade, Romain, Le Tourneau, Thierry, Messika-Zeitoun, David, Trottier, Mikaël, Tessier, Michel, Guimond, Jean, Nadeau, Maxime, Engert, James C., Khaw, Kay-Tee, Wareham, Nicholas J., Dweck, Marc R., Mathieu, Patrick, Pibarot, Philippe, Schott, Jean-Jacques, Thanassoulis, George, Clavel, Marie-Annick, Bossé, Yohan, Arsenault, Benoit J.
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547086/
https://ncbi.nlm.nih.gov/pubmed/31141105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2019.1581
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