Genetic Variation in LPA, Calcific Aortic Valve Stenosis in Patients Undergoing Cardiac Surgery, and Familial Risk of Aortic Valve Microcalcification

IMPORTANCE: Genetic variants at the LPA locus are associated with both calcific aortic valve stenosis (CAVS) and coronary artery disease (CAD). Whether these variants are associated with CAVS in patients with CAD vs those without CAD is unknown. OBJECTIVE: To study the associations of LPA variants w...

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書誌詳細
出版年:JAMA Cardiol
主要な著者: Perrot, Nicolas, Thériault, Sébastien, Dina, Christian, Chen, Hao Yu, Boekholdt, S. Matthijs, Rigade, Sidwell, Després, Audrey-Anne, Poulin, Anthony, Capoulade, Romain, Le Tourneau, Thierry, Messika-Zeitoun, David, Trottier, Mikaël, Tessier, Michel, Guimond, Jean, Nadeau, Maxime, Engert, James C., Khaw, Kay-Tee, Wareham, Nicholas J., Dweck, Marc R., Mathieu, Patrick, Pibarot, Philippe, Schott, Jean-Jacques, Thanassoulis, George, Clavel, Marie-Annick, Bossé, Yohan, Arsenault, Benoit J.
フォーマット: Artigo
言語:Inglês
出版事項: American Medical Association 2019
主題:
Original Investigation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547086/
https://ncbi.nlm.nih.gov/pubmed/31141105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2019.1581
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