Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase

Bacterial ClpB and yeast Hsp104 are homologous Hsp100 protein disaggregases that serve critical functions in proteostasis by solubilizing protein aggregates. Two AAA+ nucleotide binding domains (NBDs) power polypeptide translocation through a central channel comprised of a hexameric spiral of protom...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Rizo, Alexandrea N., Lin, JiaBei, Gates, Stephanie N., Tse, Eric, Bart, Stephen M., Castellano, Laura M., DiMaio, Frank, Shorter, James, Southworth, Daniel R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546751/
https://ncbi.nlm.nih.gov/pubmed/31160557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10150-y
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items