The Surprising Role of Amyloid Fibrils in HIV Infection

Tekijä Castellano, Laura M., Shorter, James
Julkaistu 2012

Suramin Inhibits Hsp104 ATPase and Disaggregase Activity

Tekijä Torrente, Mariana P., Castellano, Laura M., Shorter, James
Julkaistu 2014

Nicotinic Partial Agonists Varenicline and Sazetidine-A Have Differential Effects on Affective Behavior

Tekijä Turner, Jill R., Castellano, Laura M., Blendy, Julie A.
Julkaistu 2010

Parallel Anxiolytic-Like Effects and Upregulation of Neuronal Nicotinic Acetylcholine Receptors Following Chronic Nicotine and Varenicline

Tekijä Turner, Jill R., Castellano, Laura M., Blendy, Julie A.
Julkaistu 2011

Repurposing Hsp104 to antagonize seminal amyloid and counter HIV infection

Tekijä Castellano, Laura M., Bart, Stephen M., Holmes, Veronica M., Weissman, Drew, Shorter, James
Julkaisussa Chem Biol (2015)

Epigallocatechin-3-gallate rapidly remodels PAP85-120, SEM1(45-107), and SEM2(49-107) seminal amyloid fibrils

Tekijä Castellano, Laura M., Hammond, Rebecca M., Holmes, Veronica M., Weissman, Drew, Shorter, James
Julkaisussa Biol Open (2015)

Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events

Tekijä Jackrel, Meredith E., DeSantis, Morgan E., Martinez, Bryan A., Castellano, Laura M., Stewart, Rachel M., Caldwell, Kim A., Caldwell, Guy A., Shorter, James
Julkaistu 2014

Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase

Tekijä Rizo, Alexandrea N., Lin, JiaBei, Gates, Stephanie N., Tse, Eric, Bart, Stephen M., Castellano, Laura M., DiMaio, Frank, Shorter, James, Southworth, Daniel R.
Julkaisussa Nat Commun (2019)

Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases

Tekijä Durie, Clarissa L., Lin, JiaBei, Scull, Nathaniel W., Mack, Korrie L., Jackrel, Meredith E., Sweeny, Elizabeth A., Castellano, Laura M., Shorter, James, Lucius, Aaron L.
Julkaisussa Biophys J (2019)

Structure of Calcarisporiella thermophila Hsp104 disaggregase that antagonizes diverse proteotoxic misfolding events

Tekijä Michalska, Karolina, Zhang, Kaiming, March, Zachary M., Hatzos-Skintges, Catherine, Pintilie, Grigore, Bigelow, Lance, Castellano, Laura M., Miles, Leann J., Jackrel, Meredith E., Chuang, Edward, Jedrzejczak, Robert, Shorter, James, Chiu, Wah, Joachimiak, Andrzej
Julkaisussa Structure (2018)

Therapeutic genetic variation revealed in diverse Hsp104 homologs

Tekijä March, Zachary M, Sweeney, Katelyn, Kim, Hanna, Yan, Xiaohui, Castellano, Laura M, Jackrel, Meredith E, Lin, JiaBei, Chuang, Edward, Gomes, Edward, Willicott, Corey W, Michalska, Karolina, Jedrzejczak, Robert P, Joachimiak, Andrzej, Caldwell, Kim A, Caldwell, Guy A, Shalem, Ophir, Shorter, James
Julkaisussa eLife (2020)

A molecular tweezer antagonizes seminal amyloids and HIV infection

Tekijä Lump, Edina, Castellano, Laura M, Meier, Christoph, Seeliger, Janine, Erwin, Nelli, Sperlich, Benjamin, Stürzel, Christina M, Usmani, Shariq, Hammond, Rebecca M, von Einem, Jens, Gerold, Gisa, Kreppel, Florian, Bravo-Rodriguez, Kenny, Pietschmann, Thomas, Holmes, Veronica M, Palesch, David, Zirafi, Onofrio, Weissman, Drew, Sowislok, Andrea, Wettig, Burkhard, Heid, Christian, Kirchhoff, Frank, Weil, Tanja, Klärner, Frank-Gerrit, Schrader, Thomas, Bitan, Gal, Sanchez-Garcia, Elsa, Winter, Roland, Shorter, James, Münch, Jan
Julkaisussa eLife (2015)