Parallel Anxiolytic-Like Effects and Upregulation of Neuronal Nicotinic Acetylcholine Receptors Following Chronic Nicotine and Varenicline

INTRODUCTION: Clinical and preclinical studies suggest that regulation of nicotinic acetylcholine receptors (nAChR) maybe involved in the etiology of withdrawal symptoms. METHODS: We evaluated heteromeric nAChR regulation via [(3)H]epibatidine binding following cessation of chronic nicotine or varen...

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Autores principales: Turner, Jill R., Castellano, Laura M., Blendy, Julie A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001959/
https://ncbi.nlm.nih.gov/pubmed/21097981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntq206
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