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Activation of α4β2*/α6β2* Nicotinic Receptors Alleviates Anxiety during Nicotine Withdrawal Without Upregulating Nicotinic Receptors

Although nicotine mediates its effects through several nicotinic acetylcholine receptor (nAChR) subtypes, it remains to be determined which nAChR subtypes directly mediate heightened anxiety during withdrawal. Relative success in abstinence has been found with the nAChR partial agonist varenicline (...

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מידע ביבליוגרפי
Main Authors: Yohn, Nicole L., Turner, Jill R., Blendy, Julie A.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989801/
https://ncbi.nlm.nih.gov/pubmed/24627467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.211706
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