Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich’s Ataxia

Friedreich’s Ataxia (FA) is an inherited neurodegenerative disorder resulting from decreased expression of the mitochondrial protein frataxin, for which there is no approved therapy. High throughput screening of clinically used drugs identified Dimethyl fumarate (DMF) as protective in FA patient cel...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Jasoliya, Mittal, Sacca, Francesco, Sahdeo, Sunil, Chedin, Frederic, Pane, Chiara, Brescia Morra, Vincenzo, Filla, Alessandro, Pook, Mark, Cortopassi, Gino
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546270/
https://ncbi.nlm.nih.gov/pubmed/31158268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217776
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker