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Putative Structural Rearrangements Associated with the Interaction of Macrocyclic Inhibitors with Norovirus 3CL Protease

Human noroviruses are the primary cause of outbreaks of acute gastroenteritis worldwide. The problem is further compounded by the current lack of norovirus-specific antivirals or vaccines. Noroviruses have a single-stranded, positive sense 7–8 kb RNA genome which encodes a polyprotein precursor that...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proteins
Egile Nagusiak: Galasiti Kankanamalage, Anushka C., Weerawarna, Pathum M., Rathnayake, Athri D., Kim, Yunjeong, Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545144/
https://ncbi.nlm.nih.gov/pubmed/30883881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25682
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