Caricamento...

Putative Structural Rearrangements Associated with the Interaction of Macrocyclic Inhibitors with Norovirus 3CL Protease

Human noroviruses are the primary cause of outbreaks of acute gastroenteritis worldwide. The problem is further compounded by the current lack of norovirus-specific antivirals or vaccines. Noroviruses have a single-stranded, positive sense 7–8 kb RNA genome which encodes a polyprotein precursor that...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Proteins
Autori principali: Galasiti Kankanamalage, Anushka C., Weerawarna, Pathum M., Rathnayake, Athri D., Kim, Yunjeong, Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545144/
https://ncbi.nlm.nih.gov/pubmed/30883881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25682
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !