Nature-inspired design and evolution of anti-amyloid antibodies

Antibodies that recognize amyloidogenic aggregates with high conformational and sequence specificity are important for detecting and potentially treating a wide range of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. However, these types of antibodies are chal...

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Vydáno v:J Biol Chem
Hlavní autoři: Julian, Mark C., Rabia, Lilia A., Desai, Alec A., Arsiwala, Ammar, Gerson, Julia E., Paulson, Henry L., Kane, Ravi S., Tessier, Peter M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544860/
https://ncbi.nlm.nih.gov/pubmed/30918024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004731
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