Transforming growth factor–β (TGF-β)–induced up-regulation of TGF-β receptors at the cell surface amplifies the TGF-β response

Functional activation of the transforming growth factor–β (TGF-β) receptors (TGFBRs) is carefully regulated through integration of post-translational modifications, spatial regulation at the cellular level, and TGFBR availability at the cell surface. Although the bulk of TGFBRs resides inside the ce...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Duan, Dana, Derynck, Rik
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544840/
https://ncbi.nlm.nih.gov/pubmed/30948511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005763
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items