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Transforming Growth Factor-β1 (TGF-β1) Induces Human Osteoclast Apoptosis by Up-regulating Bim

Transforming growth factor-β1 (TGF-β1) is the most abundant TGF-β isoform detected in bone and is an important functional modulator of osteoclasts. TGF-β1 can induce osteoclast apoptosis; however, the apoptotic pathways involved in this process are not known. We show here that human osteoclasts expr...

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Bibliografiske detaljer
Main Authors: Houde, Nicolas, Chamoux, Estelle, Bisson, Martine, Roux, Sophie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749113/
https://ncbi.nlm.nih.gov/pubmed/19574221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019372
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