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Transforming Growth Factor-β1 (TGF-β1) Induces Human Osteoclast Apoptosis by Up-regulating Bim
Transforming growth factor-β1 (TGF-β1) is the most abundant TGF-β isoform detected in bone and is an important functional modulator of osteoclasts. TGF-β1 can induce osteoclast apoptosis; however, the apoptotic pathways involved in this process are not known. We show here that human osteoclasts expr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749113/ https://ncbi.nlm.nih.gov/pubmed/19574221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019372 |
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