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Runx1 Is a Co-activator with FOXO3 to Mediate Transforming Growth Factor β (TGFβ)-induced Bim Transcription in Hepatic Cells

Transforming growth factor β (TGFβ) regulates essential cellular functions such as cellular proliferation, differentiation, and apo pto sis. The Bcl-2 family of proteins has been implicated as mediators of TGFβ-induced apo pto sis. We demonstrated previously that TGFβ induces the expression of Bim (...

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Bibliografiske detaljer
Main Authors: Wildey, Gary M., Howe, Philip H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740449/
https://ncbi.nlm.nih.gov/pubmed/19494111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027201
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