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TRPV-5 Mediates a Receptor Activator of NF-κB (RANK) Ligand-induced Increase in Cytosolic Ca(2+) in Human Osteoclasts and Down-regulates Bone Resorption

Most of the signaling effectors located downstream of receptor activator of NF-κB (RANK) activation are calcium-sensitive. However, the early signaling events that lead to the mobilization of intracellular calcium in human osteoclasts are still poorly understood. The Ca(2+)-sensitive fluorescent pro...

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Detalhes bibliográficos
Main Authors: Chamoux, Estelle, Bisson, Martine, Payet, Marcel Daniel, Roux, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919098/
https://ncbi.nlm.nih.gov/pubmed/20547482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.075234
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