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siRNA Knock-Down of RANK Signaling to Control Osteoclast-Mediated Bone Resorption

PURPOSE: To demonstrate the ability of small interfering (si)RNA targeting the cell receptor, RANK, to control osteoclast function in cultures of both primary and secondary osteoclasts and their precursor cells. METHODS: siRNA targeting RANK was transfected into both RAW264.7 and primary bone marrow...

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Detalhes bibliográficos
Main Authors: Wang, Yuwei, Grainger, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885461/
https://ncbi.nlm.nih.gov/pubmed/20333451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0099-5
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