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siRNA-mediated knock-down of NOX3: therapy for hearing loss?
Cisplatin is a widely used chemotherapeutic agent that causes significant hearing loss. Previous studies have shown that cisplatin exposure is associated with increase in reactive oxygen species (ROS) in the cochlea. The inner ear expresses a unique isoform of NADPH oxidase, NOX3. This enzyme may be...
Gorde:
| Argitaratua izan da: | Cell Mol Life Sci |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
SP Birkhäuser Verlag Basel
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5441545/ https://ncbi.nlm.nih.gov/pubmed/22562580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1016-3 |
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