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Role of β-arrestin1/ERK MAP kinase pathway in regulating adenosine A(1) receptor desensitization and recovery
Exposure of cells to adenosine receptor (AR) agonists leads to receptor uncoupling from G proteins and downregulation of the A(1)AR. The receptor levels on the cell surface generally recover on withdrawal of the agonist, because of either translocation of the sequestered A(1)AR back to plasma membra...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806147/ https://ncbi.nlm.nih.gov/pubmed/19828838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00190.2009 |
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