Role of β-arrestin1/ERK MAP kinase pathway in regulating adenosine A(1) receptor desensitization and recovery

Exposure of cells to adenosine receptor (AR) agonists leads to receptor uncoupling from G proteins and downregulation of the A(1)AR. The receptor levels on the cell surface generally recover on withdrawal of the agonist, because of either translocation of the sequestered A(1)AR back to plasma membra...

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Detaylı Bibliyografya
Asıl Yazarlar: Jajoo, Sarvesh, Mukherjea, Debashree, Kumar, Sunny, Sheth, Sandeep, Kaur, Tejbeer, Rybak, Leonard P., Ramkumar, Vickram
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2010
Konular:
Receptors and Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806147/
https://ncbi.nlm.nih.gov/pubmed/19828838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00190.2009
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