The p62 P392L Mutation Linked to Paget’s Disease Induces Activation of Human Osteoclasts

Mutations of the gene encoding p62/SQSTM1 have been described in Paget’s disease of bone (PDB), identifying p62 as an important player in osteoclast signaling. We investigated the phenotype of osteoclasts differentiated from peripheral blood monocytes obtained from healthy donors or PDB patients, al...

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Bibliografiske detaljer
Udgivet i:Mol Endocrinol
Main Authors: Chamoux, Estelle, Couture, Julie, Bisson, Martine, Morissette, Jean, Brown, Jacques P., Roux, Sophie
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2009
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224938/
https://ncbi.nlm.nih.gov/pubmed/19589897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0066
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