The p62 P392L Mutation Linked to Paget’s Disease Induces Activation of Human Osteoclasts

Mutations of the gene encoding p62/SQSTM1 have been described in Paget’s disease of bone (PDB), identifying p62 as an important player in osteoclast signaling. We investigated the phenotype of osteoclasts differentiated from peripheral blood monocytes obtained from healthy donors or PDB patients, al...

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Dettagli Bibliografici
Pubblicato in:Mol Endocrinol
Autori principali: Chamoux, Estelle, Couture, Julie, Bisson, Martine, Morissette, Jean, Brown, Jacques P., Roux, Sophie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2009
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224938/
https://ncbi.nlm.nih.gov/pubmed/19589897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0066
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