Transforming growth factor–β (TGF-β)–induced up-regulation of TGF-β receptors at the cell surface amplifies the TGF-β response

Functional activation of the transforming growth factor–β (TGF-β) receptors (TGFBRs) is carefully regulated through integration of post-translational modifications, spatial regulation at the cellular level, and TGFBR availability at the cell surface. Although the bulk of TGFBRs resides inside the ce...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Duan, Dana, Derynck, Rik
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544840/
https://ncbi.nlm.nih.gov/pubmed/30948511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005763
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