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Mechanism of the efflux transport of demethoxycurcumin-O-glucuronides in HeLa cells stably transfected with UDP-glucuronosyltransferase 1A1

Demethoxycurcumin (DMC) is a safe and natural food-coloring additive, as well as an agent with several therapeutic properties. However, extensive glucuronidation in vivo has resulted in its poor bioavailability. In this study, we aimed to investigate the formation of DMC-O-glucuronides by uridine 5&...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Zhang, Beibei, Yang, Jing, Qin, Zifei, Li, Shishi, Xu, Jinjin, Yao, Zhihong, Zhang, Xiaojian, Gonzalez, Frank J., Yao, Xinsheng
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544300/
https://ncbi.nlm.nih.gov/pubmed/31150474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217695
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