In Vitro Glucuronidation of Wushanicaritin by Liver Microsomes, Intestine Microsomes and Expressed Human UDP-Glucuronosyltransferase Enzymes

Wushanicaritin, a natural polyphenol compound, exerts many biological activities. This study aimed to characterize wushanicaritin glucuronidation by pooled human liver microsomes (HLM), human intestine microsomes and individual uridine diphosphate-glucuronosyltransferase (UGT) enzyme. Glucuronidatio...

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Publicat a:Int J Mol Sci
Autors principals: Hong, Xiaodan, Zheng, Yuanru, Qin, Zifei, Wu, Baojian, Dai, Yi, Gao, Hao, Yao, Zhihong, Gonzalez, Frank J., Yao, Xinsheng
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618632/
https://ncbi.nlm.nih.gov/pubmed/28925930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091983
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