Metabolism and disposition of corylifol A from Psoralea corylifolia: metabolite mapping, isozyme contribution, species differences and identification of efflux transporters for corylifol A-O-glucuronide in HeLa1A1 cells

1. Corylifol A (CA), a phenolic compound from Psoralea corylifolia, possessed several biological properties but poor bioavailability. Here we aimed to investigate the roles of cytochromes P450s (CYPs), UDP-glucuronosyltransferases (UGTs) and efflux transporters in metabolism and disposition of CA. 2...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Xenobiotica
Main Authors: Li, Yang, Xu, Jinjin, Xu, Chunxia, Qin, Zifei, Li, Shishi, Hu, Liufang, Yao, Zhihong, Gonzalez, Frank J., Yao, Xinsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396962/
https://ncbi.nlm.nih.gov/pubmed/32116078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2020.1732496
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados