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Elevated VMP1 expression in acute myeloid leukemia amplifies autophagy and is protective against venetoclax-induced apoptosis
Vacuole membrane protein (VMP1) is a putative autophagy protein, which together with Beclin-1 acts as a molecular switch in activating autophagy. In the present study the role of VMP1 was analysed in CD34(+) cells of cord blood (CB) and primary acute myeloid leukemia (AML) cells and cell lines. An i...
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| Publicado en: | Cell Death Dis |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541608/ https://ncbi.nlm.nih.gov/pubmed/31142733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1648-4 |
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