Unfolding of hidden white blood cell count phenotypes for gene discovery using latent class mixed modeling

Resting-state white blood cell (WBC) count is a marker of inflammation and immune system health. There is evidence that WBC count is not fixed over time and there is heterogeneity in WBC trajectory that is associated with morbidity and mortality. Latent class mixed modeling (LCMM) is a method that c...

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Vydáno v:Genes Immun
Hlavní autoři: Hall, Taryn O., Stanaway, Ian B., Carrell, David S., Carroll, Robert J., Denny, Joshua C., Hakonarson, Hakon, Larson, Eric B., Mentch, Frank D., Peissig, Peggy L., Pendergrass, Sarah A., Rosenthal, Elizabeth A., Jarvik, Gail P., Crosslin, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541537/
https://ncbi.nlm.nih.gov/pubmed/30459343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-018-0051-y
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