Unfolding of hidden white blood cell count phenotypes for gene discovery using latent class mixed modeling

Resting-state white blood cell (WBC) count is a marker of inflammation and immune system health. There is evidence that WBC count is not fixed over time and there is heterogeneity in WBC trajectory that is associated with morbidity and mortality. Latent class mixed modeling (LCMM) is a method that c...

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Pubblicato in:Genes Immun
Autori principali: Hall, Taryn O., Stanaway, Ian B., Carrell, David S., Carroll, Robert J., Denny, Joshua C., Hakonarson, Hakon, Larson, Eric B., Mentch, Frank D., Peissig, Peggy L., Pendergrass, Sarah A., Rosenthal, Elizabeth A., Jarvik, Gail P., Crosslin, David R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541537/
https://ncbi.nlm.nih.gov/pubmed/30459343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-018-0051-y
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