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Unfolding of hidden white blood cell count phenotypes for gene discovery using latent class mixed modeling

Resting-state white blood cell (WBC) count is a marker of inflammation and immune system health. There is evidence that WBC count is not fixed over time and there is heterogeneity in WBC trajectory that is associated with morbidity and mortality. Latent class mixed modeling (LCMM) is a method that c...

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Bibliografske podrobnosti
izdano v:Genes Immun
Main Authors: Hall, Taryn O., Stanaway, Ian B., Carrell, David S., Carroll, Robert J., Denny, Joshua C., Hakonarson, Hakon, Larson, Eric B., Mentch, Frank D., Peissig, Peggy L., Pendergrass, Sarah A., Rosenthal, Elizabeth A., Jarvik, Gail P., Crosslin, David R.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541537/
https://ncbi.nlm.nih.gov/pubmed/30459343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-018-0051-y
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