Minimally toxic dose of lipopolysaccharide and α-Synuclein oligomer elicit synergistic dopaminergic neurodegeneration: role and mechanism of microglial NOX2 activation

OBJECTIVES: To investigate role and mechanism of microglial β-nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) activation in minimally toxic dose of lipopolysaccharide (LPS) and α-Synuclein (Syn)-elicited synergistic dopaminergic neurodegeneration. EXPERIMENTAL DESIGN OF THE PAPER: NOX2(...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mol Neurobiol
Autors principals: Zhang, Wei, Gao, Jun-hua, Yan, Zhao-fen, Huang, Xi-yan, Guo, Peng, Sun, Li, Liu, Zhuo, Hu, Yang, Zuo, Li-jun, Yu, Shu-yang, Cao, Chen-Jie, Wang, Xiao-min, Hong, Jau-shyong
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538260/
https://ncbi.nlm.nih.gov/pubmed/27975175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-0308-2
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars