No Dose Adjustment for Isavuconazole Based on Age or Sex

This phase 1, open-label, single-dose, parallel-group study evaluated the pharmacokinetics (PK) of isavuconazole after a single oral dose of the prodrug isavuconazonium sulfate in healthy nonelderly (age, 18 to 45 years) and elderly (age, ≥65 years) males and females. Overall, 48 subjects were enrol...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Desai, Amit V., Han, David, Kowalski, Donna L., Lademacher, Christopher, Pearlman, Helene, Yamazaki, Takao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535513/
https://ncbi.nlm.nih.gov/pubmed/30962330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02629-18
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