Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults

This report summarizes phase 1 studies that evaluated pharmacokinetic interactions between the novel triazole antifungal agent isavuconazole and the immunosuppressants cyclosporine, mycophenolic acid, prednisolone, sirolimus, and tacrolimus in healthy adults. Healthy subjects received single oral do...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Groll, Andreas H., Desai, Amit, Han, David, Howieson, Corrie, Kato, Kota, Akhtar, Shahzad, Kowalski, Donna, Lademacher, Christopher, Lewis, William, Pearlman, Helene, Mandarino, Debra, Yamazaki, Takao, Townsend, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298005/
https://ncbi.nlm.nih.gov/pubmed/27273343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.284
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