Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults

This report summarizes phase 1 studies that evaluated pharmacokinetic interactions between the novel triazole antifungal agent isavuconazole and the immunosuppressants cyclosporine, mycophenolic acid, prednisolone, sirolimus, and tacrolimus in healthy adults. Healthy subjects received single oral do...

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Gepubliceerd in:Clin Pharmacol Drug Dev
Hoofdauteurs: Groll, Andreas H., Desai, Amit, Han, David, Howieson, Corrie, Kato, Kota, Akhtar, Shahzad, Kowalski, Donna, Lademacher, Christopher, Lewis, William, Pearlman, Helene, Mandarino, Debra, Yamazaki, Takao, Townsend, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298005/
https://ncbi.nlm.nih.gov/pubmed/27273343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.284
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