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Pharmacokinetic and Pharmacodynamic Evaluation of the Drug‐Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects

This phase 1 trial evaluated pharmacokinetic and pharmacodynamic interactions between the novel triazole antifungal agent isavuconazole and warfarin in healthy adults. Multiple doses of isavuconazole were administered as the oral prodrug, isavuconazonium sulfate (372 mg 3 times a day for 2 days load...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Pharmacol Drug Dev
Päätekijät: Desai, Amit, Yamazaki, Takao, Dietz, Albert J., Kowalski, Donna, Lademacher, Christopher, Pearlman, Helene, Akhtar, Shahzad, Townsend, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298089/
https://ncbi.nlm.nih.gov/pubmed/27278712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.283
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