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Pharmacokinetic Interaction Between Isavuconazole and a Fixed‐Dose Combination of Lopinavir 400 mg/Ritonavir 100 mg in Healthy Subjects

This phase 1, open‐label study evaluated the pharmacokinetic effects of coadministration of the antifungal agent, isavuconazole (administered as its water‐soluble prodrug isavuconazonium sulfate), with the antiretroviral agent lopinavir/ritonavir in healthy adults. In part 1, 13 subjects were random...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Yamazaki, Takao, Desai, Amit, Han, David, Kato, Kota, Kowalski, Donna, Akhtar, Shahzad, Lademacher, Christopher, Kovanda, Laura, Townsend, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297880/
https://ncbi.nlm.nih.gov/pubmed/27273248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.282
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