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Pharmacokinetic Interaction Between Isavuconazole and a Fixed‐Dose Combination of Lopinavir 400 mg/Ritonavir 100 mg in Healthy Subjects

This phase 1, open‐label study evaluated the pharmacokinetic effects of coadministration of the antifungal agent, isavuconazole (administered as its water‐soluble prodrug isavuconazonium sulfate), with the antiretroviral agent lopinavir/ritonavir in healthy adults. In part 1, 13 subjects were random...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Pharmacol Drug Dev
Prif Awduron: Yamazaki, Takao, Desai, Amit, Han, David, Kato, Kota, Kowalski, Donna, Akhtar, Shahzad, Lademacher, Christopher, Kovanda, Laura, Townsend, Robert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297880/
https://ncbi.nlm.nih.gov/pubmed/27273248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.282
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