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Identification of the IL-33 protein segment that controls subcellular localization, extracellular secretion, and functional maturation
Proteolytic activation of the IL-33 precursor, full-length interleukin-33 (FLIL33), at multiple sites within the sensor domain (aa 95 – 109) yields several functionally mature (MIL33) forms. Unlike nuclear FLIL33, intracellular MIL33 occurs in the cytoplasm, is secreted from source cells, and exerts...
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| Publicat a: | Cytokine |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535307/ https://ncbi.nlm.nih.gov/pubmed/30856600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2019.02.015 |
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