The full-length interleukin-33 (FLIL33)–importin-5 interaction does not regulate nuclear localization of FLIL33 but controls its intracellular degradation

Human mature IL-33 is a member of the IL-1 family and a potent regulator of immunity through its pro-T helper cell 2 activity. Its precursor form, full-length interleukin-33 (FLIL33), is an intranuclear protein in many cell types, including fibroblasts, and its intracellular levels can change in res...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Clerman, Andrew, Noor, Zahid, Fishelevich, Rita, Lockatell, Virginia, Hampton, Brian S., Shah, Nirav G., Salcedo, Mariah V., Todd, Nevins W., Atamas, Sergei P., Luzina, Irina G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766934/
https://ncbi.nlm.nih.gov/pubmed/29127199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807636
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